Epididymitis Causes, Symptoms, & Treatment Options

Epididymitis: Causes, Symptoms, & Treatment Options

Epididymitis can cause sudden or gradually increasing pain and swelling in the scrotum, making everyday activities uncomfortable and sometimes worrying. 

It is usually caused by an infection or inflammation of the epididymis, a small tube located behind each testicle. The good news is that most cases improve with appropriate treatment.

Understanding the common causes, symptoms, diagnosis, and treatment options can help you recognize the condition early and know when medical care is needed.

Table of Contents

What Is Epididymitis?

Epididymitis is swelling and inflammation of the epididymis. The epididymis is a small, coiled tube located behind each testicle. It stores and carries sperm.

Epididymitis usually affects one side of the scrotum, but it can sometimes affect both sides. It may start suddenly or develop slowly over time.

When symptoms last for less than six weeks, it is called acute epididymitis. When symptoms continue for six weeks or longer, it may be called chronic epididymitis.

Testicular or scrotal pain can have many causes. Some, such as testicular torsion, need urgent treatment. That is why it is important to see a healthcare professional rather than assuming the pain is caused by epididymitis.

What Causes Epididymitis?

The cause often depends on a person’s age, sexual activity, medical history, and other risk factors.

Common causes include:

  • Sexually transmitted infections (STIs): In sexually active men, bacteria such as Chlamydia trachomatis and Neisseria gonorrhoeae are common causes.
  • Urinary tract infections: Bacteria from the urinary tract can sometimes spread to the epididymis.
  • Prostate or urinary problems: Conditions that interfere with normal urine flow may increase the risk of infection.
  • Certain procedures: Urinary catheterization or procedures involving the urinary tract can occasionally contribute to infection.
  • Noninfectious inflammation: Injury, strenuous activity, or urine flowing backward into the epididymis can sometimes cause inflammation without a bacterial infection.

In children and older adults, the causes may differ from those commonly seen in younger sexually active men.

Who Is at Risk of Developing Epididymitis?

Anyone with male reproductive anatomy can develop epididymitis, but certain factors can increase the likelihood.

Risk factors include:

  • Having unprotected sex or multiple sexual partners
  • Having an untreated STI
  • A history of urinary tract infections
  • Enlarged prostate or other urinary problems
  • Recent urinary tract procedures
  • Use of a urinary catheter
  • Previous episodes of epididymitis
  • Certain physical injuries or activities that put pressure on the groin

Practicing safer sex and treating urinary or genital infections promptly can reduce the risk.

How Does It Affect Fertility?

Epididymitis does not usually cause permanent infertility, particularly when it is diagnosed and treated early. However, severe, repeated, or untreated infections can sometimes cause scarring in the epididymis.

This scarring may interfere with the movement of sperm from the testicle. Fertility problems are more concerning when inflammation affects both sides or when complications develop.

If you are having difficulty conceiving after an episode of epididymitis, a doctor or fertility specialist clinic can assess sperm production and movement with tests such as a semen analysis.

Epididymitis Symptoms

Symptoms can appear gradually or develop relatively quickly. Common signs include:

  • Pain or tenderness in one side of the scrotum
  • Swelling or enlargement of the scrotum
  • Warm or reddened scrotal skin
  • Pain that may extend into the groin or lower abdomen
  • Burning or pain when urinating
  • Frequent or urgent urination
  • Discharge from the penis
  • Pain during ejaculation
  • Blood in the semen
  • Fever or chills

Some people have only mild symptoms, while others experience significant pain and swelling.

Sudden, severe testicular pain requires urgent medical attention because testicular torsion can cut off blood flow to the testicle and needs emergency treatment.

How Is Epididymitis Diagnosed?

A healthcare professional will usually begin by asking about your symptoms, sexual history, urinary symptoms, and medical history.

A physical examination can help identify swelling, tenderness, and other changes in the scrotum.

Depending on the situation, tests may include:

  • Urine testing to look for signs of infection
  • STI testing using urine or genital samples
  • Blood tests when an infection needs further evaluation
  • Ultrasound, particularly when testicular torsion or another cause of scrotal pain needs to be ruled out

An accurate diagnosis matters because treatment depends on the underlying cause.

Epididymitis Treatment Options

Treatment depends on whether the condition is caused by a bacterial infection or another form of inflammation.

Antibiotics

Bacterial epididymitis is generally treated with antibiotics.

The specific medication depends on the suspected cause, including whether an STI is involved. It is important to take the prescribed course exactly as directed, even if symptoms begin improving.

If an STI caused the infection, sexual partners may also need testing and treatment.

Pain Relief and Support

Doctors may recommend measures to reduce discomfort, such as:

  • Resting and limiting strenuous activity
  • Supporting or elevating the scrotum
  • Applying a cold pack wrapped in a cloth
  • Using appropriate over-the-counter pain medicine when safe to do so

People with severe symptoms or complications may require additional treatment or hospital care.

How Long Does Epididymitis Take to Go Away?

Symptoms often begin improving within a few days after appropriate treatment, but complete recovery can take longer.

Pain, swelling, or tenderness may continue for several weeks even after the infection has been treated.

If symptoms are not improving or become worse after starting treatment, contact your healthcare professional.

Persistent symptoms may mean that another condition is present or that further evaluation is needed.

Can Epididymitis Be Treated at Home?

Home care can help manage symptoms, but it should not replace medical evaluation when an infection is suspected.

Rest, scrotal support, cold packs, and appropriate pain relief may make you more comfortable while prescribed treatment takes effect. However, use antibiotics only when a healthcare professional recommends them.

Avoid self-treating with leftover antibiotics because the wrong medication may not treat the underlying infection and can make future infections more difficult to manage.

Epididymitis and Sexual Health

When epididymitis is caused by an STI, sexual health becomes an important part of treatment.

Avoid sexual activity until your healthcare professional advises that it is safe, particularly when an STI is suspected or confirmed. Current and recent sexual partners may need testing and treatment to prevent reinfection.

Using condoms consistently can lower the risk of many sexually transmitted infections and may help reduce the risk of STI-related epididymitis.

Possible Complications of Epididymitis

Most people recover without serious long-term problems when epididymitis is treated appropriately. However, complications can occur, especially when treatment is delayed.

Possible complications include:

  • An abscess or collection of pus
  • Chronic epididymal pain
  • Recurrent epididymitis
  • Infection spreading to nearby structures
  • Testicular inflammation (epididymo-orchitis)
  • Scarring that may affect sperm transport
  • Rarely, fertility problems

Prompt medical care can reduce the likelihood of these complications.

How to Prevent Epididymitis

Not every case can be prevented, but several steps can lower your risk:

  • Practice safer sex and use condoms.
  • Get tested for STIs when appropriate.
  • Complete treatment for diagnosed infections.
  • Seek care for persistent urinary symptoms.
  • Follow medical instructions after urinary procedures.
  • Avoid sexual contact until an STI-related infection has been treated and you have been advised that it is safe.

Regular sexual health care is particularly important if you have a higher risk of STI exposure.

When to See a Doctor for Epididymitis

See a fertility specialist if you develop testicular or scrotal pain, swelling, urinary discomfort, penile discharge, or other symptoms that could indicate an infection.

Seek emergency medical attention for sudden or severe testicular pain, especially if it develops quickly or is accompanied by nausea, vomiting, or a testicle that appears unusually positioned.

These symptoms can occur with testicular torsion, which is a medical emergency.

Final Thoughts

Epididymitis is a treatable condition, but scrotal pain should never be ignored. Infections, including sexually transmitted infections and urinary infections, are common causes. 

Noninfectious inflammation can have other triggers. Early diagnosis helps identify the underlying cause and start appropriate treatment.

If symptoms include sudden severe testicular pain, seek urgent care rather than trying to diagnose or treat the problem at home.